Interactor 1: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2
Interactor 2: ADA2A (P08913)
Alpha-2A adrenergic receptor (Alpha-2 adrenergic receptor subtype C10) (Alpha-2A adrenoreceptor) (Alpha-2A adrenoceptor) (Alpha-2AAR)
Gene: ADRA2A
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 15782186 |
Identification Methods | fluorescent resonance energy transfer |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | 7tm_1~G-alpha |
Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and 3 others more... |
Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024