HitPredict

Interactor 1: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	17110338, 29924966, 26618866
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1480
+	Hs
		444657 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528614 GNA11_HUMAN (1-354): 2.62e-162: 459: 50.42		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528513 GNAZ_HUMAN (1-354): 6.56e-160: 453: 66.38		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528938 GNAS2_HUMAN (1-355): 1.94e-147: 423: 38.83		CFTR_HUMAN (1-1480): 0: 1031: 100.00