HitPredict

Interactor 1: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2

Interactor 2: DUS22 (Q9NRW4)
Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x)
Gene: DUSP22

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 184
+	Hs
		926719 GNAI1_HUMAN (1-355): 8.33e-178: 498: 87.89		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		444799 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		451043 GNAO_HUMAN (1-355): 1.03e-173: 488: 69.30		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		391454 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		837651 GNAQ_HUMAN (1-354): 8.04e-165: 466: 50.42		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		391386 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		DUS4_HUMAN (4-161): 4.72e-59: 190: 31.45
+	Hs
		391406 GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26
+	Hs
		670490 GNA11_HUMAN (1-354): 2.62e-162: 459: 50.42		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		444775 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		926689 GNAI1_HUMAN (1-355): 8.33e-178: 498: 87.89		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26
+	Hs
		325971 GNA14_HUMAN (3-354): 2.08e-158: 449: 49.86		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		444739 GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26
+	Hs
		1053443 GNA13_HUMAN (2-354): 4.58e-153: 437: 39.72		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		670484 GNA11_HUMAN (1-354): 2.62e-162: 459: 50.42		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		926593 GNAS2_HUMAN (1-355): 1.94e-147: 423: 38.83		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26