HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	33961781, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 156
+	Hs
		470331 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924034 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924049 H2A3_HUMAN (1-130): 3.34e-68: 203: 99.23		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		555403 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		470332 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924322 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924334 H2A3_HUMAN (1-130): 3.34e-68: 203: 99.23		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924374 H2A1C_HUMAN (1-130): 3.23e-68: 203: 98.46		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		391644 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924387 H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		924397 H2A1J_HUMAN (1-128): 1.18e-67: 201: 97.66		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		474085 H2A2A_RAT (1-130): 2.9e-68: 203: 96.92		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		555404 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Sc
		392251 H2A2_YEAST (16-128): 1.02e-59: 181: 79.65		RL40A_YEAST (1-125): 2.07e-42: 139: 64.00
+	Hs
		474911 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		1092092 H2A6_ARATH (1-128): 8.02e-60: 182: 70.54		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Dm
		950447 H2A_DROME (17-125): 3.74e-60: 182: 88.99		R9PY16_DROME (1-68): 7.11e-29: 108: 91.18