HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32251276
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 1912
+	Hs
		470387 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059795 H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059717 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059647 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		555466 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		391675 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018640 H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		229279 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		229433 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		391728 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		CHD9_HUMAN (111-1653): 0: 783: 22.99
+	Hs
		229296 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		470278 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		SMCA1_HUMAN (617-1597): 0: 779: 27.44
+	Hs
		555306 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		SMCA1_HUMAN (617-1597): 0: 779: 27.44
+	Hs
		391915 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		555654 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		151474 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		CHD2_HUMAN (493-1689): 0: 739: 30.57
+	Hs
		1151349 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		CHD1L_HUMAN (722-1232): 4.81e-118: 399: 44.04
+	Hs
		1185203 H2A3_HUMAN (1-130): 3.34e-68: 203: 99.23		CHD1L_HUMAN (722-1232): 4.81e-118: 399: 44.04
+	Hs
		470439 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		CHD1L_HUMAN (722-1232): 4.81e-118: 399: 44.04
+	Hs
		555532 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		CHD1L_HUMAN (722-1232): 4.81e-118: 399: 44.04