HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.655

Property	Details
Experiments	12813456, 10891493, 11830591
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 832
+	Mm
		1151749 H2A2A_MOUSE (1-130): 2.9e-68: 203: 96.92		KAT2B_MOUSE (1-832): 0: 1161: 91.13
+	Hs
		1087073 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		KAT2B_HUMAN (72-832): 0: 1128: 100.00
+	Hs
		391824 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		KAT2A_HUMAN (63-832): 0: 1056: 73.42
+	Hs
		1087072 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		KAT2A_HUMAN (63-832): 0: 1056: 73.42
+	Mm
		70932 H2A3_MOUSE (1-130): 3.34e-68: 203: 99.23		EP300_MOUSE (664-825): 2.37e-35: 147: 23.03
+	Hs
		391554 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Hs
		631492 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Hs
		1067005 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		555299 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Hs
		555434 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BPTF_HUMAN (725-825): 5.43e-35: 146: 47.53
+	Hs
		1067038 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		243783 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		244795 H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		244848 H2A1J_HUMAN (1-128): 1.18e-67: 201: 97.66		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		1066979 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		244634 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		555470 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		391768 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		PB1_HUMAN (683-826): 4.92e-18: 91.8: 22.00
+	Hs
		1087035 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		PB1_HUMAN (683-826): 4.92e-18: 91.8: 22.00
+	Hs
		1087066 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		PHIP_HUMAN (683-826): 5.4e-15: 81.7: 24.49