HitPredict

Interactor 1: H2A2 (P04910)
Histone H2A-beta (H2A.2)
Gene: hta2

Interactor 2: H2B1 (P04913)
Histone H2B-alpha (H2B.1)
Gene: htb1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	27890612
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0140463 - chromatin-protein adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sp			1 126
+	Hs
		1087239 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B2E_HUMAN (4-124): 6.09e-49: 154: 71.07
+	Hs
		1216239 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B1H_HUMAN (4-124): 3.52e-49: 154: 71.07
+	Hs
		707681 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B1B_HUMAN (4-124): 1.67e-48: 153: 70.25
+	Hs
		918497 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B1C_HUMAN (4-124): 1.26e-48: 153: 71.07
+	Hs
		886151 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B1D_HUMAN (5-124): 3.11e-48: 152: 70.83
+	Hs
		617950 H2A2C_HUMAN (1-130): 3.72e-59: 180: 78.46		H2B1O_HUMAN (4-124): 1.95e-49: 155: 71.07
+	Hs
		617974 H2AJ_HUMAN (1-130): 4.84e-59: 180: 78.46		H2B1O_HUMAN (4-124): 1.95e-49: 155: 71.07
+	Hs
		1087007 H2A2C_HUMAN (1-130): 3.72e-59: 180: 78.46		H2B2E_HUMAN (4-124): 6.09e-49: 154: 71.07
+	Hs
		1087075 H2A2C_HUMAN (1-130): 3.72e-59: 180: 78.46		H2B1H_HUMAN (4-124): 3.52e-49: 154: 71.07
+	Hs
		1087377 H2AJ_HUMAN (1-130): 4.84e-59: 180: 78.46		H2B2E_HUMAN (4-124): 6.09e-49: 154: 71.07
+	Hs
		1216224 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B3B_HUMAN (4-124): 4.5e-47: 149: 69.42
+	Hs
		886117 H2A2C_HUMAN (1-130): 3.72e-59: 180: 78.46		H2B1D_HUMAN (5-124): 3.11e-48: 152: 70.83
+	Hs
		886186 H2AJ_HUMAN (1-130): 4.84e-59: 180: 78.46		H2B1D_HUMAN (5-124): 3.11e-48: 152: 70.83
+	Xl
		355252 Q6AZJ8_XENLA (1-129): 5.76e-59: 179: 76.74		H2B11_XENLA (4-124): 8.53e-48: 151: 70.25
+	Hs
		1087049 H2A2C_HUMAN (1-130): 3.72e-59: 180: 78.46		H2B3B_HUMAN (4-124): 4.5e-47: 149: 69.42
+	Ce
		452191 H2A_CAEEL (1-127): 3.23e-59: 180: 78.74		H2B4_CAEEL (21-124): 4.89e-47: 149: 75.96
+	Hs
		1216241 H2A2B_HUMAN (1-129): 1.6e-60: 184: 79.85		H2B1A_HUMAN (3-124): 2.05e-43: 140: 69.67
+	At
		188587 H2A6_ARATH (1-130): 1.34e-61: 186: 70.00		H2B6_ARATH (2-124): 2.28e-41: 135: 62.99
+	Hs
		1087076 H2A2C_HUMAN (1-130): 3.72e-59: 180: 78.46		H2B1A_HUMAN (3-124): 2.05e-43: 140: 69.67
+	Sc
		355290 H2A2_YEAST (1-131): 1.28e-58: 179: 81.82		H2B1_YEAST (2-126): 2.66e-40: 132: 78.91