HitPredict

Interactor 1: H2A1 (P04911)
Histone H2A.1
Gene: HTA1

Interactor 2: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.80	0.751

Property	Details
Experiments	8779721, 18158899, 19217406
Identification Methods	coimmunoprecipitation, experimental interaction detection, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 978
+	Sc
		392240 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		SIR3_YEAST (1-978): 0: 937: 100.00
+	Sc
		392178 H2A1_YEAST (1-132): 2.22e-62: 188: 100.00		ORC1_YEAST (1-975): 0: 754: 23.77
+	Sc
		392528 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		ORC1_YEAST (1-975): 0: 754: 23.77
+	Hs
		1033386 H2A2C_HUMAN (3-130): 2.4e-62: 188: 73.44		ORC1_HUMAN (179-959): 3.67e-175: 533: 13.85
+	Hs
		391577 H2A1B_HUMAN (3-129): 1.67e-62: 189: 74.02		RFC1_HUMAN (129-771): 6.79e-26: 117: 12.24
+	Sc
		392530 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		ORC4_YEAST (490-896): 8.62e-16: 83.5: 8.37
+	Sc
		392415 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		RFC1_YEAST (265-769): 2.54e-14: 79.7: 10.46