HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: SPT5 (P27692)
Transcription elongation factor SPT5 (Chromatin elongation factor SPT5)
Gene: SPT5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	35102600, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 1063
+	Sc
		392070 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		SPT5_YEAST (1-1063): 0: 803: 100.00
+	Hs
		123831 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		SPT5H_HUMAN (125-1060): 0: 781: 23.54
+	Hs
		123844 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		SPT5H_HUMAN (125-1060): 0: 781: 23.54
+	Hs
		554260 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		MUC1_HUMAN (749-1059): 1.53e-14: 80.8: 10.06
+	Hs
		391929 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		MDN1_HUMAN (30-582): 8.01e-09: 62.3: 10.61
+	Hs
		555663 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		MDN1_HUMAN (30-582): 8.01e-09: 62.3: 10.61