HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: SPT16 (P32558)
FACT complex subunit SPT16 (Cell division control protein 68) (Facilitates chromatin transcription complex subunit SPT16) (Suppressor of Ty protein 16)
Gene: SPT16

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.956

Property	Details
Experiments	23499444, 24248595, 24352239, 16554755, 19106085, 37968396, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~Rtt106, Histone_H2A_C~Rtt106
Common GO terms	GO:0006281 - DNA repair GO:0006325 - chromatin organization GO:0031298 - replication fork protection complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 1035
+	Sc
		392084 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		SPT16_YEAST (1-1035): 0: 1136: 100.00
+	Hs
		1312248 H2AJ_HUMAN (3-130): 3.28e-63: 190: 73.44		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Hs
		1087145 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Hs
		1151400 H2A2A_HUMAN (3-128): 7.37e-63: 189: 75.40		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Hs
		1185216 H2A3_HUMAN (3-128): 9.58e-63: 189: 75.40		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Hs
		391984 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Hs
		470626 H2A1_HUMAN (3-128): 1.07e-62: 189: 75.40		SP16H_HUMAN (4-1028): 0: 1082: 32.76
+	Mm
		650195 H2AX_MOUSE (3-125): 2.02e-61: 186: 77.24		SP16H_MOUSE (4-1028): 0: 1085: 32.38
+	Hs
		555708 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		SP16H_HUMAN (4-1028): 0: 1082: 32.76