HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: UBP10 (P53874)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: UBP10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	29288197, 37968396
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Sc			1 792
+	Sc
		392173 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		UBP10_YEAST (1-770): 5.85e-168: 506: 100.00
+	Hs
		777047 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP8_HUMAN (9-736): 4.31e-125: 403: 16.25
+	Hs
		1087135 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP22_HUMAN (280-738): 2.61e-104: 332: 19.34
+	Hs
		391971 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		UBP22_HUMAN (280-738): 2.61e-104: 332: 19.34
+	Hs
		271018 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		UBP2_HUMAN (167-737): 1.17e-99: 322: 15.68
+	Hs
		271104 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP2_HUMAN (167-737): 1.17e-99: 322: 15.68
+	Hs
		1058217 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP10_HUMAN (11-734): 1.63e-93: 312: 15.96
+	Hs
		1087027 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP51_HUMAN (300-736): 1.36e-94: 312: 20.26
+	Hs
		391756 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		UBP51_HUMAN (300-736): 1.36e-94: 312: 20.26
+	Hs
		1087074 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP7_HUMAN (162-786): 4e-90: 308: 13.21
+	Hs
		391829 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		UBP7_HUMAN (162-786): 4e-90: 308: 13.21
+	Hs
		259285 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP12_HUMAN (344-734): 2.97e-91: 292: 22.36
+	Hs
		391991 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		UBP3_HUMAN (255-739): 1.58e-88: 290: 18.47
+	Hs
		1151394 H2A2A_HUMAN (3-128): 7.37e-63: 189: 75.40		UBP21_HUMAN (363-736): 1.15e-87: 289: 20.16
+	Hs
		905382 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP46_HUMAN (340-733): 1.57e-86: 280: 20.98
+	Hs
		1312240 H2AJ_HUMAN (3-130): 3.28e-63: 190: 73.44		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		391943 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Sc
		392536 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		UBP3_YEAST (16-734): 4.12e-79: 275: 15.39
+	Sc
		392501 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		UBP8_YEAST (330-731): 1.97e-74: 251: 19.72
+	Hs
		1087139 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		UBP20_HUMAN (462-738): 2.62e-24: 111: 30.51