HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: SWR1 (Q05471)
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1)
Gene: SWR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	26116819, 37968396
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Sc			1 1514
+	Sc
		392201 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		SWR1_YEAST (1-1514): 0: 1057: 100.00
+	Hs
		1087132 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		INO80_HUMAN (210-1444): 0: 644: 23.37
+	Hs
		391964 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		INO80_HUMAN (210-1444): 0: 644: 23.37
+	Hs
		229433 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69
+	Hs
		229279 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69
+	Hs
		229296 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69
+	Hs
		1018640 H2A1H_HUMAN (3-128): 3.42e-63: 190: 75.40		CHD3_HUMAN (1017-1463): 2.27e-80: 296: 24.89
+	Hs
		391675 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		CHD3_HUMAN (1017-1463): 2.27e-80: 296: 24.89
+	Hs
		391915 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		CHD8_HUMAN (1034-1508): 5.26e-80: 295: 23.70
+	Hs
		391728 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		CHD9_HUMAN (1108-1510): 5.26e-78: 288: 26.18
+	Hs
		391846 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		EP400_HUMAN (1098-1509): 2.23e-76: 284: 27.52
+	Hs
		470278 H2A1_HUMAN (3-128): 1.07e-62: 189: 75.40		SMCA1_HUMAN (1060-1503): 5.31e-78: 283: 26.51
+	Hs
		555306 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		SMCA1_HUMAN (1060-1503): 5.31e-78: 283: 26.51
+	Hs
		555358 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		SMCA2_HUMAN (1090-1484): 4.11e-73: 272: 23.89
+	Sc
		392595 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		ISW2_YEAST (1093-1503): 1.18e-72: 267: 25.94
+	Hs
		555359 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		SMCA4_HUMAN (1036-1496): 9.82e-72: 267: 19.60
+	Sc
		392293 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		SNF2_YEAST (1246-1416): 1.73e-34: 147: 47.43
+	Sc
		392052 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		SNF2_YEAST (1246-1416): 1.73e-34: 147: 47.43
+	Sc
		392509 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		INO80_YEAST (997-1198): 1.6e-22: 107: 8.53
+	Sc
		392161 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		INO80_YEAST (997-1198): 1.6e-22: 107: 8.53