Interactor 1: PRIO (P04925)
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: Prnp

Interactor 2: PRIO (P04925)
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: Prnp

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 19805070, 21041683, 21441913, 22854022, 22449963, 20345906, 23892077
Identification Methods electron microscopy, x-ray fiber diffraction, cosedimentation in solution, transmission electron microscopy, atomic force microscopy, aggregation assay, circular dichroism, fluorescence technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Prion~Prion
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001933 - negative regulation of protein phosphorylation
GO:0002020 - protease binding
GO:0005507 - copper ion binding
GO:0005521 - lamin binding
and 63 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 254
Mm

1 254
+ Hs
+ Oc
+ Bt
+ Cl

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024