HitPredict

Interactor 1: PRIO (P04925)
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: Prnp

Interactor 2: NECT1 (Q9JKF6)
Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)
Gene: Nectin1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15146195
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Prion~V-set
Common GO terms	GO:0016020 - membrane GO:0030425 - dendrite GO:0038023 - signaling receptor activity GO:0044877 - protein-containing complex binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 254 Mm			1 515
+	Mm
		103587 PRIO_MOUSE (1-254): 7.54e-165: 457: 100.00		G5E8G3_MOUSE (4-369): 1.03e-64: 215: 18.28
+	Mm
		392789 PRIO_MOUSE (1-254): 7.54e-165: 457: 100.00		CADM3_MOUSE (40-402): 1.39e-63: 213: 20.33
+	Mm
		392790 PRIO_MOUSE (1-254): 7.54e-165: 457: 100.00		NTRI_MOUSE (4-354): 6.74e-61: 205: 18.75
+	Mm
		392780 PRIO_MOUSE (1-254): 7.54e-165: 457: 100.00		Q8BG33_MOUSE (13-354): 5.52e-59: 200: 18.54
+	Mm
		392757 PRIO_MOUSE (1-254): 7.54e-165: 457: 100.00		NCAM1_MOUSE (140-515): 6.88e-41: 159: 10.20
+	Hs
		377903 PRIO_HUMAN (1-254): 1.02e-126: 361: 85.10		NCAM1_HUMAN (32-506): 6.15e-60: 213: 14.11
+	Mm
		192272 PRIO_MOUSE (1-254): 7.54e-165: 457: 100.00		NCAM2_MOUSE (117-341): 3.2e-17: 87.2: 20.00
+	Hs
		378064 PRIO_HUMAN (1-254): 1.02e-126: 361: 85.10		MYLK_HUMAN (142-246): 1.49e-10: 66.3: 11.43