HitPredict

Interactor 1: AT1A1 (P05023)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: ATP1A1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	32357304, 35063084
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030424 - axon GO:0045121 - membrane raft GO:0051087 - protein-folding chaperone binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1023 Hs			1 758
+	Rn
		416147 AT1A1_RAT (1-1023): 0: 1141: 96.77		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94112 AT1A1_RAT (1-1023): 0: 1141: 96.77		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		496196 AT1A3_HUMAN (26-1023): 0: 1085: 87.88		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496589 AT1A2_HUMAN (1-1023): 0: 1084: 86.71		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		416169 AT1A3_RAT (28-1023): 0: 1083: 87.75		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94114 AT1A3_RAT (28-1023): 0: 1083: 87.75		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Rn
		416161 AT1A2_RAT (1-1023): 0: 1081: 86.61		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94113 AT1A2_RAT (1-1023): 0: 1081: 86.61		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		496237 AT2A2_HUMAN (42-1012): 0: 779: 26.90		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		513722 AT2A2_RAT (42-1012): 0: 778: 26.80		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94131 AT2A2_RAT (42-1012): 0: 778: 26.80		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		223146 AT2A2_MOUSE (42-1012): 0: 779: 26.61		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		561576 AT2A2_HUMAN (42-1012): 0: 779: 26.90		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57