HitPredict

Interactor 1: AT1A1 (P05023)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: ATP1A1

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30024968, 32900848
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016323 - basolateral plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1023 Hs			1 236
+	Hs
		393138 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		393037 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		326007 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326018 AT1A3_HUMAN (26-1023): 0: 1085: 87.88		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Mm
		783907 AT12A_MOUSE (21-1023): 0: 946: 66.04		CD63_MOUSE (1-232): 2.72e-51: 168: 24.18
+	Hs
		1274499 AT2A3_HUMAN (43-1012): 0: 770: 27.05		TSN17_HUMAN (8-235): 5.76e-55: 178: 21.37
+	Hs
		163865 AT2A1_HUMAN (43-1012): 0: 777: 26.65		TSN33_HUMAN (9-233): 7.63e-51: 168: 22.78
+	Hs
		326165 AT2A3_HUMAN (43-1012): 0: 770: 27.05		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326054 AT2C1_HUMAN (45-880): 3.62e-114: 376: 31.46		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48