HitPredict

Interactor 1: AT1B1 (P05026)
Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)
Gene: ATP1B1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 303 Hs			1 758
+	Rn
		427144 AT1B1_RAT (1-303): 2.58e-152: 430: 94.74		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94119 AT1B1_RAT (1-303): 2.58e-152: 430: 94.74		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		497915 AT1B1_MOUSE (1-303): 7.65e-153: 431: 93.75		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		496211 AT1B2_HUMAN (4-301): 5.56e-117: 340: 38.00		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496638 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		497916 AT1B2_MOUSE (4-301): 6.78e-116: 337: 37.67		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		534588 AT1B1_MOUSE (1-303): 7.65e-153: 431: 93.75		MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63