HitPredict

Interactor 1: AT1B1 (P05026)
Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)
Gene: ATP1B1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0016020 - membrane GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 303 Hs			1 192
+	Hs
		393414 AT1B1_HUMAN (1-303): 8.13e-156: 438: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		393483 AT1B1_HUMAN (1-303): 8.13e-156: 438: 100.00		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		393407 AT1B1_HUMAN (1-303): 8.13e-156: 438: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		872002 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564461 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545284 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		872097 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		871994 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		872005 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		871995 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		871996 AT1B3_HUMAN (10-303): 2.09e-104: 307: 33.78		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98