HitPredict

Interactor 1: PNP (P05055)
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
Gene: PNP

Interactor 2: PNP (P05055)
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
Gene: PNP

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 15236960, 16858726
Identification Methods mass spectrometry studies of complexes, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains KH_1~KH_1, KH_1~RNase_PH, KH_1~S1, PNPase~PNPase, PNPase~RNase_PH, PNPase~RNase_PH_C, RNase_PH~RNase_PH, RNase_PH~RNase_PH_C, RNase_PH~S1, RNase_PH_C~RNase_PH_C, S1~S1
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000287 - magnesium ion binding
GO:0003723 - RNA binding
GO:0004654 - polyribonucleotide nucleotidyltransferase activity
GO:0005829 - cytosol
and 7 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 711
Ec

1 711
+ Sa
+ At
+ Hs
+ Hs
+ Hs
+ Ec
+ At
+ Dm
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Ss

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Last updated: 15 Jul 2024