Interactor 1: TOLC (P02930)
Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC)
Gene: TOLC

Interactor 2: ACRB (P31224)
Multidrug efflux pump subunit AcrB (AcrAB-TolC multidrug efflux pump subunit AcrB) (Acridine resistance protein B)
Gene: ACRB

Species: Escherichia coli K-12

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.55 0.632

The method score is based on:

Property Details
Experiments 29176613, 15228545, 15155734
Identification Methods affinity chromatography technology, cross-linking study, cosedimentation through density gradient
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0009410 - response to xenobiotic stimulus
GO:0009636 - response to toxic substance
GO:0015125 - bile acid transmembrane transporter activity
GO:0015562 - efflux transmembrane transporter activity
GO:0015721 - bile acid and bile salt transport
and 7 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025