Interactor 1: ACTN1 (P05094)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: VINC (P12003)
Vinculin (Metavinculin)
Gene: VCL

Species: Gallus gallus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.539

The method score is based on:

Property Details
Experiments 8037676
Identification Methods pull down, far western blotting, electron microscopy, cosedimentation in solution
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001725 - stress fiber
GO:0005886 - plasma membrane
GO:0005915 - zonula adherens
GO:0005925 - focal adhesion
GO:0017166 - vinculin binding
and 9 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 893
Gg

1 1135
+ Hs
+ Dm
+ Ce
+ Hs
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024