Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: CD177 (Q8N6Q3)
CD177 antigen (Human neutrophil alloantigen 2a) (HNA-2a) (NB1 glycoprotein) (NB1 GP) (Polycythemia rubra vera protein 1) (PRV-1) (CD antigen CD177)
Gene: CD177

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 21193407
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007159 - leukocyte cell-cell adhesion
GO:0032930 - positive regulation of superoxide anion generation
and 7 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 769
Hs

1 437
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024