Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12208882
Identification Methods enzyme linked immunosorbent assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_beta~V-set
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007160 - cell-matrix adhesion
GO:0034113 - heterotypic cell-cell adhesion
GO:0098609 - cell-cell adhesion
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 769
Hs

1 310
+ Hs
+ Hs
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024