HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 973
+	Hs
		615205 S10A1_HUMAN (1-90): 8.66e-33: 110: 36.17		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		685156 S10AB_HUMAN (2-93): 1.23e-31: 108: 26.04		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		642918 S10A4_HUMAN (1-93): 4.07e-31: 106: 27.84		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		638928 S100P_HUMAN (2-92): 1.25e-30: 105: 35.79		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		661206 S10A2_HUMAN (1-92): 1.72e-29: 102: 26.04		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689707 S100Z_HUMAN (1-93): 1.81e-29: 102: 28.87		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689700 S10A3_HUMAN (1-90): 1.52e-28: 100: 22.34		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		416365 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689702 S10AA_HUMAN (1-93): 5.15e-28: 98.7: 25.77		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		380746 S100B_HUMAN (2-89): 3.95e-27: 96.4: 32.61		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		416580 S10A6_HUMAN (1-88): 9.59e-27: 95.3: 24.44		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689703 S10AC_HUMAN (2-89): 4.03e-26: 93.7: 38.04		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689699 S10A5_HUMAN (1-91): 7.64e-25: 90.6: 29.35		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689708 S10AD_HUMAN (2-80): 4.4e-21: 81.4: 23.75		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689709 S10AE_HUMAN (3-80): 1.13e-20: 80.2: 20.25		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		666669 S100G_HUMAN (5-80): 2.17e-18: 74.1: 32.47		NAC1_HUMAN (1-973): 0: 1131: 100.00
+	Hs
		689706 S1A7A_HUMAN (3-91): 1.56e-17: 72.5: 24.21		NAC1_HUMAN (1-973): 0: 1131: 100.00