HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: RNF5 (Q99942)
E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1)
Gene: RNF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30232010, 32614325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008270 - zinc ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 180
+	Hs
		416501 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		RNF5_HUMAN (1-164): 8.79e-56: 175: 100.00
+	Hs
		661388 S10A2_HUMAN (1-92): 1.72e-29: 102: 26.04		TRI11_HUMAN (14-148): 2.69e-31: 119: 17.78
+	Hs
		416677 S10A6_HUMAN (1-88): 9.59e-27: 95.3: 24.44		TRI11_HUMAN (14-148): 2.69e-31: 119: 17.78
+	Hs
		416494 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		RN170_HUMAN (12-133): 1.15e-26: 103: 22.48
+	Mm
		437546 S10AA_MOUSE (1-93): 8.47e-29: 100: 25.77		HLTF_MOUSE (20-77): 4.61e-21: 91.3: 29.31
+	Hs
		893794 S10AA_HUMAN (1-93): 5.15e-28: 98.7: 25.77		HLTF_HUMAN (20-77): 5.99e-21: 90.9: 29.31
+	Hs
		416629 S10A6_HUMAN (1-88): 9.59e-27: 95.3: 24.44		LONF2_HUMAN (10-73): 5.87e-11: 62.1: 32.84