Interactor 1: IL4 (P05112)
Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (BSF-1) (Binetrakin) (Lymphocyte stimulatory factor 1) (Pitrakinra)
Gene: IL4

Interactor 2: IRF4 (Q15306)
Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (Multiple myeloma oncogene 1) (NF-EM5)
Gene: IRF4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 12374808
Identification Methods electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0032733 - positive regulation of interleukin-10 production
GO:0032736 - positive regulation of interleukin-13 production
GO:0042110 - T cell activation
GO:0043011 - myeloid dendritic cell differentiation
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 153
Hs

1 451
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024