HitPredict

Interactor 1: PAI1 (P05121)
Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)
Gene: SERPINE1

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.50	0.593

Property	Details
Experiments	9606191, 10092624, 19139564
Identification Methods	electrophoretic mobility supershift assay, electrophoretic mobility shift assay, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 402 Hs			1 552
+	Hs
		344193 A1AT_HUMAN (23-402): 2.92e-143: 415: 28.46		SMAD4_HUMAN (1-552): 0: 696: 100.00
+	Hs
		397101 PAI1_HUMAN (1-402): 2.14e-164: 468: 100.00		SMAD3_HUMAN (19-549): 1.96e-176: 506: 31.22
+	Hs
		167324 PAI1_HUMAN (1-402): 2.14e-164: 468: 100.00		SMAD7_HUMAN (33-137): 4.06e-26: 112: 28.45