HitPredict

Interactor 1: ADT2 (P05141)
ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene: SLC25A5

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	31980649, 21706016, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 217
+	Hs
		518313 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		518121 ADT1_HUMAN (1-297): 1.24e-113: 331: 89.23		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		411572 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		397303 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CSK_HUMAN (2-139): 3.92e-24: 100: 36.24
+	Hs
		397256 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		518236 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		518227 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		924934 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00