HitPredict

Interactor 1: ADT2 (P05141)
ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene: SLC25A5

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	21370995, 24725412
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 2527
+	Hs
		1123866 Q59EI9_HUMAN (1-296): 4.12e-115: 336: 92.57		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		518382 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3090 A0A0S2Z3H3_HUMAN (1-297): 1.24e-113: 331: 89.23		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		518152 ADT1_HUMAN (1-297): 1.24e-113: 331: 89.23		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1121048 Q53GR7_HUMAN (2-271): 1.29e-45: 164: 20.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		73279 B4E290_HUMAN (98-297): 6.41e-45: 160: 23.27		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130213 Q6NVC0_HUMAN (105-297): 7.29e-38: 138: 22.77		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		397303 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74
+	Zm
		20092 A0A1D6HIF7_MAIZE (141-296): 2.57e-12: 68.3: 16.39		A0A1D6QQC6_MAIZE (1885-2141): 1.05e-24: 115: 31.27