HitPredict

Interactor 1: ADT2 (P05141)
ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene: SLC25A5

Interactor 2: SMUF2 (Q9HAU4)
E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)
Gene: SMURF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23973329
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 748
+	Hs
		518491 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		SMUF2_HUMAN (1-748): 0: 834: 100.00
+	Hs
		397518 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		SMUF1_HUMAN (1-748): 0: 748: 70.44
+	Hs
		397430 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		HUWE1_HUMAN (114-747): 0: 589: 31.46
+	Hs
		518401 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		HUWE1_HUMAN (114-747): 0: 589: 31.46
+	Sc
		576006 ADT2_YEAST (207-297): 5.21e-12: 67.1: 26.32		TOM1_YEAST (325-747): 1.36e-156: 505: 40.47
+	Hs
		125082 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		WWP2_HUMAN (1-416): 7.64e-26: 116: 17.39
+	Hs
		518515 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		HECW2_HUMAN (19-281): 8.01e-17: 87.5: 14.80