HitPredict

Interactor 1: IPSP (P05154)
Plasma serine protease inhibitor (Acrosomal serine protease inhibitor) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Protein C inhibitor) (PCI) (Serpin A5)
Gene: SERPINA5

Interactor 2: KLK2 (P20151)
Kallikrein-2 (EC 3.4.21.35) (Glandular kallikrein-1) (hGK-1) (Tissue kallikrein-2)
Gene: KLK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9016396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Serpin~Trypsin
Common GO terms	GO:0005576 - extracellular region GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 261
+	Hs
		397629 IPSP_HUMAN (1-406): 3.48e-172: 488: 100.00		KLK3_HUMAN (1-261): 1.45e-115: 333: 77.01
+	Hs
		344274 AACT_HUMAN (7-406): 1.07e-161: 462: 46.31		KLK2_HUMAN (1-261): 7.7e-123: 352: 100.00
+	Hs
		344148 A1AT_HUMAN (6-406): 9.76e-161: 460: 43.07		KLK1_HUMAN (1-260): 3.01e-118: 340: 65.90
+	Hs
		344149 A1AT_HUMAN (6-406): 9.76e-161: 460: 43.07		KLK3_HUMAN (1-261): 1.45e-115: 333: 77.01
+	Mm
		430527 A1AT1_MOUSE (25-406): 2.77e-154: 443: 40.67		Q9Z1R9_MOUSE (2-260): 8.17e-118: 338: 41.70
+	Hs
		344349 AACT_HUMAN (7-406): 1.07e-161: 462: 46.31		KLK13_HUMAN (1-259): 7.75e-108: 314: 44.65
+	Hs
		371463 IPSP_HUMAN (1-406): 3.48e-172: 488: 100.00		KLKB1_HUMAN (15-259): 2.13e-92: 286: 33.85
+	Hs
		589593 SPB6_HUMAN (40-406): 4.31e-140: 406: 32.28		KLK2_HUMAN (1-261): 7.7e-123: 352: 100.00
+	Hs
		428671 SPB8_HUMAN (41-406): 4.69e-141: 408: 32.63		TRY1_HUMAN (2-260): 5.4e-118: 339: 42.09
+	Hs
		344097 ANT3_HUMAN (24-406): 1.03e-138: 405: 28.46		KLK1_HUMAN (1-260): 3.01e-118: 340: 65.90
+	Hs
		420739 KAIN_HUMAN (36-406): 3.91e-137: 400: 46.17		KLK1_HUMAN (1-260): 3.01e-118: 340: 65.90
+	Hs
		344172 A1AT_HUMAN (6-406): 9.76e-161: 460: 43.07		CTRL_HUMAN (12-260): 5.28e-92: 273: 34.62
+	Hs
		719387 SPB6_HUMAN (40-406): 4.31e-140: 406: 32.28		KLK13_HUMAN (1-259): 7.75e-108: 314: 44.65
+	Mm
		1141519 SPB6_MOUSE (40-406): 9.62e-143: 413: 31.48		KLK8_MOUSE (4-257): 1.14e-104: 305: 44.88
+	Hs
		344256 A1AT_HUMAN (6-406): 9.76e-161: 460: 43.07		KLK4_HUMAN (23-260): 4.68e-52: 171: 40.17
+	Hs
		198328 A1AT_HUMAN (6-406): 9.76e-161: 460: 43.07		KLK10_HUMAN (28-260): 7.17e-45: 154: 39.49
+	Hs
		198377 CBG_HUMAN (28-406): 2.87e-147: 425: 41.10		KLK10_HUMAN (28-260): 7.17e-45: 154: 39.49
+	Hs
		198417 SPB10_HUMAN (41-406): 3.44e-144: 417: 32.66		KLK10_HUMAN (28-260): 7.17e-45: 154: 39.49
+	Hs
		341268 ANT3_HUMAN (24-406): 1.03e-138: 405: 28.46		FA9_HUMAN (23-255): 1.34e-37: 139: 35.63
+	Hs
		344100 ANT3_HUMAN (24-406): 1.03e-138: 405: 28.46		GRAA_HUMAN (24-257): 1.25e-37: 134: 37.04