HitPredict

Interactor 1: IC1 (P05155)
Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1)
Gene: SERPING1

Interactor 2: C1S (P09871)
Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain]
Gene: C1S

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 6604523, 17488724
Identification Methods biochemical, comigration in sds page
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~Serpin, Serpin~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006958 - complement activation, classical pathway
GO:0045087 - innate immune response
GO:0072562 - blood microparticle
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024