Interactor 1: IC1 (P05155)
Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1)
Gene: SERPING1

Interactor 2: ITIH4 (Q14624)
Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]
Gene: ITIH4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 24981860
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0062023 - collagen-containing extracellular matrix
GO:0070062 - extracellular exosome
GO:0072562 - blood microparticle
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 500
Hs

1 930
+ Hs
+ Hs

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Last updated: 15 Jul 2024