Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: MX1 (P20591)
Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]
Gene: MX1

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 16009940
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus
GO:0034340 - response to type I interferon
GO:0045071 - negative regulation of viral genome replication
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 165
Hs

1 662
+ At
+ At
+ At
+ At
+ Sc
+ Rn
+ Dm
+ Rn
+ Mm

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Last updated: 15 Jul 2024