HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)
Gene: PSMA5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34599178
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 241
+	Hs
		475369 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA5_HUMAN (1-241): 1.49e-107: 311: 100.00
+	At
		188696 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA2A_ARATH (3-241): 4.07e-95: 280: 31.80
+	At
		1091773 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA2B_ARATH (3-241): 3.74e-94: 277: 31.80
+	Hs
		474930 UBB_HUMAN (3-157): 6.34e-67: 205: 32.26		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		475359 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		156205 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17
+	Hs
		475358 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	Hs
		475547 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93
+	At
		286456 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA4A_ARATH (3-240): 2.67e-89: 265: 37.55
+	At
		286449 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA6A_ARATH (4-241): 1.95e-88: 263: 32.92
+	Hs
		397786 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		156201 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17
+	Hs
		397785 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	Hs
		397877 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA6_HUMAN (4-241): 1.93e-88: 263: 25.93
+	Hs
		171476 UBD_HUMAN (15-157): 1.31e-40: 135: 24.32		PSA2_HUMAN (3-241): 3.37e-89: 265: 30.96
+	Hs
		156170 UBD_HUMAN (15-157): 1.31e-40: 135: 24.32		PSA7_HUMAN (8-239): 7.45e-89: 264: 36.17
+	Hs
		171475 UBD_HUMAN (15-157): 1.31e-40: 135: 24.32		PSA1_HUMAN (3-241): 1.03e-88: 264: 28.81
+	At
		189234 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA7B_ARATH (6-220): 4.9e-43: 147: 39.63
+	Sc
		477138 UBI4P_YEAST (3-157): 4.74e-62: 197: 32.26		PSA3_YEAST (8-238): 3.6e-44: 150: 36.40
+	At
		672527 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA7A_ARATH (6-220): 1.96e-42: 145: 39.17