Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15
Interactor 2: UBA7 (P41226)
Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (EC 6.2.1.-) (D8) (Ubiquitin-activating enzyme E1 homolog)
Gene: UBA7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 16189514, 32296183, 33961781, 22693631, 34599178, 16884686, 16009940, 14976209, 20975683, 17597759, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, comigration in sds page, unspecified method, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ThiF~ubiquitin |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019941 - modification-dependent protein catabolic process GO:0032020 - ISG15-protein conjugation and 1 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
