HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: AHNK (Q09666)
Neuroblast differentiation-associated protein AHNAK (Desmoyokin)
Gene: AHNAK

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33024031, 16009940
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 5890
+	Hs
		398026 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		AHNK2_HUMAN (1312-5890): 4.73e-94: 347: 18.49
+	At
		1092118 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		Q9LIE8_ARATH (4802-5781): 3.27e-26: 122: 9.65
+	Hs
		92115 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		NACAM_HUMAN (661-2669): 1.53e-31: 140: 10.65
+	Hs
		152577 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		KMT2D_HUMAN (237-1114): 7.49e-16: 88.5: 8.88
+	Hs
		475943 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		OTOG_HUMAN (3735-4368): 7.85e-16: 88.2: 11.68
+	Hs
		924367 RL40_HUMAN (3-82): 1.77e-34: 119: 27.50		TITIN_HUMAN (55-1917): 1.95e-40: 170: 11.08
+	Mm
		103617 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		G5E8K8_MOUSE (2-120): 7.27e-33: 128: 90.76
+	Hs
		398152 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PRC2C_HUMAN (88-2130): 5.88e-13: 78.8: 8.44
+	Rn
		1144063 UBC_RAT (2-110): 2.29e-33: 125: 28.44		SYNJ1_RAT (176-678): 3.62e-16: 89.2: 11.07