Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 15764595, 14557267, 11907205, 15107417, 9488451, 17236232, 10805757, 10585427, 20357099, 20581830
Identification Methods anti tag coimmunoprecipitation, electrophoretic mobility shift assay, electrophoretic mobility supershift assay, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0032728 - positive regulation of interferon-beta production
GO:0045087 - innate immune response
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 165
Hs

1 427
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Last updated: 15 Jul 2024