HitPredict

Interactor 1: PCCA (P05165)
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)
Gene: PCCA

Interactor 2: PCCB (P05166)
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)
Gene: PCCB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 28514442, 24981860, 33961781, 20725044
Identification Methods affinity chromatography technology, electron microscopy, pull down, molecular sieving, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Biotin_carb_C~Carboxyl_trans, Biotin_lipoyl~Carboxyl_trans, Carboxyl_trans~PCC_BT
Common GO terms GO:0004658 - propionyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
and 4 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 728
Hs

1 539
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024