HitPredict

Interactor 1: CP1A2 (P05177)
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
Gene: CYP1A2

Interactor 2: NCPR (P16435)
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)
Gene: POR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	9398194, 15680923
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Flavodoxin_1~p450
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0006805 - xenobiotic metabolic process GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 516 Hs			1 677
+	Hs
		514663 CP2C9_HUMAN (32-494): 3.49e-156: 455: 27.99		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		513728 CP2A6_HUMAN (9-512): 2.83e-153: 448: 27.90		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		560163 CP2CJ_HUMAN (31-494): 1.77e-152: 446: 27.51		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		398437 CP2E1_HUMAN (17-510): 1.31e-148: 436: 28.34		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		443995 CP3A4_HUMAN (42-512): 2.55e-147: 433: 20.17		NCPR_HUMAN (1-677): 0: 975: 100.00
+	Hs
		496154 CP2D6_HUMAN (59-486): 2.88e-64: 218: 32.34		NCPR_HUMAN (1-677): 0: 975: 100.00
+	At
		221551 C71AD_ARATH (38-510): 2.6e-152: 446: 22.29		NCPR1_ARATH (31-676): 0: 716: 36.45