Interactor 1: CP2E1 (P05181)
Cytochrome P450 2E1 (EC 1.14.14.1) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J)
Gene: CYP2E1

Interactor 2: NCPR (P16435)
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)
Gene: POR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 9398194, 15680923, 15980100
Identification Methods pull down, protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Flavodoxin_1~p450
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006805 - xenobiotic metabolic process
GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 493
Hs

1 677
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024