Interactor 1: PPB1 (P05187)
Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)
Gene: ALPP

Interactor 2: PPBI (P09923)
Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1)
Gene: ALPI

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Alk_phosphatase~Alk_phosphatase
Common GO terms GO:0000287 - magnesium ion binding
GO:0004035 - alkaline phosphatase activity
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
GO:0016311 - dephosphorylation
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 535
Hs

1 528
+ Hs
+ Hs
+ Sc
+ Sp

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Last updated: 15 Jul 2024