Interactor 1: IF2A (P05198)
Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)
Gene: EIF2S1
Interactor 2: IF2G (P41091)
Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene: EIF2S3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.93 | 1.00 | 0.965 |
The method score is based on:
Property | Details |
---|---|
Experiments | 35271311, 35031321, 30699057, 33961781, 35235311, 34349018, 37071682, 16288713 |
Identification Methods | affinity chromatography technology, cross-linking study, enzyme linked immunosorbent assay, anti tag coimmunoprecipitation |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | EIF_2_alpha~GTP_EFTU, EIF_2_alpha~GTP_EFTU_D2 |
Common GO terms | GO:0003743 - translation initiation factor activity GO:0005829 - cytosol GO:0005850 - eukaryotic translation initiation factor 2 complex GO:0006413 - translational initiation GO:0070062 - extracellular exosome |
Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024