Interactor 1: IF2A (P05198)
Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)
Gene: EIF2S1
Interactor 2: E2AK3 (Q9NZJ5)
Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)
Gene: EIF2AK3
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16720581 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~S1 |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane GO:0032057 - negative regulation of translational initiation in response to stress GO:0034198 - cellular response to amino acid starvation and 3 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
