HitPredict

Interactor 1: HMGN2 (P05204)
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
Gene: HMGN2

Interactor 2: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28514442, 24981860, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031492 - nucleosomal DNA binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 130
+	Hs
		398895 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46
+	Hs
		398923 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2A1C_HUMAN (1-130): 8.04e-68: 202: 98.46
+	Hs
		391496 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46
+	Hs
		398938 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22
+	Hs
		398933 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2A1H_HUMAN (1-128): 4.17e-67: 200: 100.00
+	Hs
		130220 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00
+	Hs
		130269 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22
+	Hs
		130258 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62
+	Hs
		130250 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92