HitPredict

Interactor 1: HMGN2 (P05204)
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
Gene: HMGN2

Interactor 2: PARP2 (Q9UGN5)
Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-)
Gene: PARP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	28514442, 33961781, 21812934
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, protein array
Interaction Type	physical association, association, adp ribosylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 583
+	Hs
		130284 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		PARP2_HUMAN (16-583): 0: 739: 100.00
+	Hs
		398809 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		PARP1_HUMAN (15-583): 0: 681: 37.91
+	Hs
		130218 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		PARP1_HUMAN (15-583): 0: 681: 37.91