HitPredict

Interactor 1: TBA1B (P05213)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin 2) (Alpha-tubulin isotype M-alpha-2) (Tubulin alpha-2 chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: Tuba1b

Interactor 2: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule GO:0045121 - membrane raft
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 451 Mm			1 733
+	Mm
		498002 TBA1A_MOUSE (1-440): 0: 715: 99.55		TAU_MOUSE (1-733): 4.79e-86: 288: 100.00
+	Mm
		498012 TBB5_MOUSE (1-439): 0: 699: 41.23		TAU_MOUSE (1-733): 4.79e-86: 288: 100.00
+	Rn
		582020 TBA1B_RAT (1-440): 0: 717: 100.00		TAU_RAT (1-733): 1.67e-78: 268: 88.46
+	Rn
		94246 TBA1B_RAT (1-440): 0: 717: 100.00		F1LST4_RAT (1-732): 4.29e-78: 268: 88.58
+	Hs
		497515 TBA1C_HUMAN (1-451): 0: 728: 98.00		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		496818 TBA4A_HUMAN (1-450): 0: 719: 96.44		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		496817 TBA1B_HUMAN (1-440): 0: 717: 100.00		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		497220 TBA1A_HUMAN (1-440): 0: 715: 99.55		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		497683 TBA8_HUMAN (1-440): 0: 701: 90.68		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		427983 TBB5_HUMAN (1-439): 0: 699: 41.23		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		496819 TBB4B_HUMAN (1-437): 0: 697: 40.96		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		503294 TBA1A_HUMAN (1-440): 0: 715: 99.55		MTAP2_HUMAN (15-733): 2.73e-32: 137: 24.15
+	Hs
		965128 TBA1A_HUMAN (1-440): 0: 715: 99.55		ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10
+	Hs
		428145 TBB5_HUMAN (1-439): 0: 699: 41.23		ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10
+	Hs
		92120 TBA1A_HUMAN (1-440): 0: 715: 99.55		NACAM_HUMAN (9-712): 2.85e-17: 88.9: 9.38
+	Hs
		653957 TBA1B_HUMAN (1-440): 0: 717: 100.00		MAP4_HUMAN (1-718): 9.04e-11: 67.7: 9.49
+	Mm
		649204 TBA1A_MOUSE (1-440): 0: 715: 99.55		MAP4_MOUSE (26-724): 1.54e-10: 66.9: 10.81
+	Hs
		1175103 TBA1A_HUMAN (1-440): 0: 715: 99.55		CHAP1_HUMAN (4-391): 9.65e-09: 60.7: 9.85