Interactor 1: IL6 (P05231)
Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2)
Gene: IL6

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 19122653, 20457835, 21602809, 22096605, 24012417, 25888873
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006954 - inflammatory response
GO:0008284 - positive regulation of cell population proliferation
GO:0010575 - positive regulation of vascular endothelial growth factor production
GO:0010628 - positive regulation of gene expression
GO:0019221 - cytokine-mediated signaling pathway
and 10 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 212
Hs

1 551
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024