HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: FBXL6 (Q8N531)
F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A)
Gene: FBXL6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_6~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 648 Hs			1 539
+	At
		1427108 Y5181_ARATH (10-622): 5.72e-161: 486: 15.77		PXL1_ARATH (119-475): 2.79e-32: 134: 13.02
+	At
		87922 Y5182_ARATH (2-643): 4.31e-165: 497: 15.80		Y3804_ARATH (80-490): 1.01e-26: 117: 12.80
+	At
		88732 Y4245_ARATH (3-643): 3.02e-157: 477: 16.14		IRK_ARATH (45-468): 1.45e-31: 131: 13.58
+	At
		88386 Y2289_ARATH (10-644): 4.67e-156: 473: 17.06		IRK_ARATH (45-468): 1.45e-31: 131: 13.58
+	At
		99918 F4I065_ARATH (2-643): 7.52e-170: 509: 17.05		TDR_ARATH (105-411): 1.95e-19: 94.4: 10.85
+	At
		88165 Y2289_ARATH (10-644): 4.67e-156: 473: 17.06		Y1743_ARATH (100-516): 3.77e-31: 130: 11.85
+	At
		1376486 BAK1_ARATH (77-647): 8.22e-158: 469: 17.30		IRK_ARATH (45-468): 1.45e-31: 131: 13.58
+	At
		88176 BAK1_ARATH (77-647): 8.22e-158: 469: 17.30		Y1743_ARATH (100-516): 3.77e-31: 130: 11.85
+	At
		88409 Y2289_ARATH (10-644): 4.67e-156: 473: 17.06		BRL2_ARATH (91-467): 9.48e-28: 120: 10.58
+	At
		88382 Y2289_ARATH (10-644): 4.67e-156: 473: 17.06		Y3804_ARATH (80-490): 1.01e-26: 117: 12.80
+	At
		1422693 IOS1_ARATH (2-643): 1.31e-154: 470: 15.97		BRL1_ARATH (155-490): 7.58e-27: 117: 12.47
+	At
		1376505 BAK1_ARATH (77-647): 8.22e-158: 469: 17.30		BRL1_ARATH (155-490): 7.58e-27: 117: 12.47
+	At
		89303 F4I065_ARATH (2-643): 7.52e-170: 509: 17.05		RGI2_ARATH (89-297): 1.51e-12: 72.5: 10.55
+	At
		99904 F4I065_ARATH (2-643): 7.52e-170: 509: 17.05		RGI4_ARATH (351-536): 1.58e-12: 72.5: 16.00
+	At
		1422679 IOS1_ARATH (2-643): 1.31e-154: 470: 15.97		BRL3_ARATH (333-536): 2.51e-20: 97.1: 14.71
+	At
		1376479 BAK1_ARATH (77-647): 8.22e-158: 469: 17.30		BRL3_ARATH (333-536): 2.51e-20: 97.1: 14.71
+	At
		89117 Y5169_ARATH (2-630): 3.32e-152: 463: 17.32		BRL3_ARATH (333-536): 2.51e-20: 97.1: 14.71
+	At
		103582 Y2451_ARATH (1-644): 6.6e-159: 480: 16.04		RGI4_ARATH (351-536): 1.58e-12: 72.5: 16.00
+	At
		103563 BAK1_ARATH (77-647): 8.22e-158: 469: 17.30		RGI4_ARATH (351-536): 1.58e-12: 72.5: 16.00
+	At
		89011 Y5129_ARATH (76-608): 5.75e-154: 459: 17.38		RGI4_ARATH (351-536): 1.58e-12: 72.5: 16.00