HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	16045761, 25609649
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 443
+	Hs
		121664 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43
+	Hs
		402026 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01
+	Hs
		121914 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80
+	Hs
		401924 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		402413 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25
+	Hs
		121674 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43
+	Hs
		569743 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01
+	Hs
		121926 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80
+	Hs
		570018 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25